What Does Clopidogrel Do To Your Body?

What are the side effects of clopidogrel 75 mg?

Common side effects of clopidogrel can include:headaches or dizziness.nausea.diarrhoea or constipation.indigestion (dyspepsia)stomach ache or abdominal pain.nosebleeds.increased bleeding (your blood taking longer to clot – for example, when you cut yourself), or easy bruising..

Does clopidogrel affect blood pressure?

Arterial hypertension is associated with platelet activation, increased sCD40L levels and endothelial dysfunction suggesting that inhibition of platelet-derived sCD40L release may improve endothelial function and lower blood pressure (BP).

Can clopidogrel cause tiredness?

Clopidogrel may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: excessive tiredness. headache.

Which is better aspirin or clopidogrel?

Clopidogrel is another guideline‐recommended antiplatelet agent21 and has been shown to be superior to aspirin in preventing composite vascular events and reducing hemorrhagic complications in a randomized controlled trial, CAPRIE (Clopidogrel versus Aspirin in Patients at Risk of Ischaemic Events).

What foods should you avoid if you are on blood thinners?

While eating small amounts of foods that are rich in vitamin K shouldn’t cause a problem, avoid consuming large amounts of certain foods or drinks, including: Kale. Spinach. Brussels sprouts.

What foods should I avoid when taking clopidogrel?

There’s a risk that you could get a stomach ulcer. Is there any food or drink I need to avoid? Do not drink grapefruit juice while taking clopidogrel. Grapefruit juice may increase the blood-thinning effect of your medicine.

What is the best time to take clopidogrel?

You can take clopidogrel at whatever time of day you find easiest to remember, but take your doses at the same time of day each day. Most people prefer to take it in the morning, as they find this helps them to remember to take it regularly. You can take the tablet either before or after a meal.

Does clopidogrel cause joint pain?

Arthralgia and backache are also known to occur with its use. There have been case reports linking arthritis with the use of clopidogrel. We describe the case of a 64-year-old man who reported symptoms of fever and joint pains following initiation of therapy with clopidogrel. Acute-phase reactants were elevated.

Is it OK to take clopidogrel every other day?

Conclusions: Long term dual anti-platelet therapy with aspirin 81 mg daily and clopidogrel 75 mg every other day beyond 12 months after PCI with DES may be a safe and efficacious cost-saving strategy to prevent VLST.

How long does clopidogrel stay in your system?

Plavix should be cleared from your system in about 33 hours. After a single, oral dose of 75 mg, Plavix (clopidogrel) has a half-life of approximately 6 hours. It takes 5.5 x half-life of a medicine for it to be out of one’s system, therefore Plavix should be eliminated from your system in 5.5 x 6 = 33 hours.

Can I drink coffee with clopidogrel?

Conclusions: Acute caffeine administration after clopidogrel loading appears to be associated with enhanced platelet inhibition 2 to 4 hours after clopidogrel intake. The mechanism probably involves synergistic increase in cAMP levels.

Does clopidogrel affect the kidneys?

Conclusions. In summary, among patients hospitalized with ACS and treated with clopidogrel, lower levels of kidney function were associated with a greater risk of death, hospitalization for AMI, and major bleeding.

What foods are good to eat when you are on blood thinners?

Leafy vegetables (e.g. kale, collards, turnip greens, swiss chard, salad greens, parsley, spinach) are the highest sources of vitamin K. Other vegetables, egg yolk, soybeans, soybean and canola oils, and some nuts also provide vitamin K at lower levels. Fruit is not a significant source of vitamin K.

Can you take clopidogrel long term?

Safety Announcement. [ 11-06-2015 ] A U.S. Food and Drug Administration (FDA) review has determined that long-term use of the blood-thinning drug Plavix (clopidogrel) does not increase or decrease overall risk of death in patients with, or at risk for, heart disease.

Does clopidogrel cause leg cramps?

You may have muscle pain while you’re taking Plavix. It’s not known for sure why this occurs in people taking the drug. If you have severe muscle pain while you’re taking Plavix, call your doctor right away. They can check to see what’s causing your discomfort, and they’ll recommend whether you need medical treatment.