Quick Answer: What Happens If I Take Too Many Clopidogrel?

Does clopidogrel affect the kidneys?

Conclusions.

In summary, among patients hospitalized with ACS and treated with clopidogrel, lower levels of kidney function were associated with a greater risk of death, hospitalization for AMI, and major bleeding..

Does clopidogrel affect the liver?

The severity of liver injury associated with clopidogrel ranges from transient, mild serum enzyme elevations to clinically apparent acute hepatitis that can be severe and lead to death. Most cases resolve with drug withdrawal within 1 to 3 months.

Is there an alternative to clopidogrel?

1). Besides oral anticoagulants, such as warfarin and the more recent dabigatran[9], and niche agents, such as cilostazol and ticlopidine[10,11], the most promising alternatives to clopidogrel in those with background aspirin therapy are prasugrel and ticagrelor.

How long should you be on clopidogrel?

The key question for your doctor is whether the benefits outweigh the extra risk. This combination treatment is prescribed for a limited period of time, usually up to a maximum of 12 months. After this period, your specialist will usually advise you to stop 1 of the 2 antiplatelet medications.

What color is urine when your kidneys are failing?

When kidneys are failing, the increased concentration and accumulation of substances in urine lead to a darker color which may be brown, red or purple. The color change is due to abnormal protein or sugar, high levels of red and white blood cells, and high numbers of tube-shaped particles called cellular casts.

Can I exercise while taking blood thinners?

Don’t be afraid to stay active. Regular physical activity is healthy, so don’t stop your favorite exercise routines because you’re using blood thinners.

What happens if I take 2 clopidogrel?

Accidentally taking 1 or 2 extra tablets is unlikely to harm you. But the amount of clopidogrel that can lead to overdose is different from person to person. Contact your doctor straight away if you have taken some extra tablets and notice any signs of bleeding.

How long does it take for clopidogrel to get out of your system?

by Drugs.com After a single, oral dose of 75 mg, Plavix (clopidogrel) has a half-life of approximately 6 hours. It takes 5.5 x half-life of a medicine for it to be out of one’s system, therefore Plavix should be eliminated from your system in 5.5 x 6 = 33 hours.

Is it OK to take clopidogrel every other day?

Conclusions: Long term dual anti-platelet therapy with aspirin 81 mg daily and clopidogrel 75 mg every other day beyond 12 months after PCI with DES may be a safe and efficacious cost-saving strategy to prevent VLST.

Should clopidogrel be taken in the morning or evening?

You can take clopidogrel at whatever time of day you find easiest to remember, but take your doses at the same time of day each day. Most people prefer to take it in the morning, as they find this helps them to remember to take it regularly. You can take the tablet either before or after a meal.

What foods should you avoid if you are on blood thinners?

Blood thinners: Eat fewer foods with vitamin KAsparagus.Broccoli.Brussels sprouts.Cauliflower.Green onions.Kale.Parsley.Spinach.

Can you overdose on clopidogrel?

Clopidogrel Overdose If you take too much clopidogrel call your healthcare provider or local Poison Control Center, or seek emergency medical attention right away. If clopidogrel is administered by a healthcare provider in a medical setting, it is unlikely that an overdose will occur.

Does clopidogrel cause joint pain?

Arthralgia and backache are also known to occur with its use. There have been case reports linking arthritis with the use of clopidogrel. We describe the case of a 64-year-old man who reported symptoms of fever and joint pains following initiation of therapy with clopidogrel. Acute-phase reactants were elevated.

Does clopidogrel make you tired?

Clopidogrel may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: excessive tiredness. headache.

Is clopidogrel better than aspirin?

Clopidogrel is another guideline‐recommended antiplatelet agent21 and has been shown to be superior to aspirin in preventing composite vascular events and reducing hemorrhagic complications in a randomized controlled trial, CAPRIE (Clopidogrel versus Aspirin in Patients at Risk of Ischaemic Events).

Can I drink coffee with Plavix?

Conclusions. Acute caffeine administration after clopidogrel loading appears to be associated with enhanced platelet inhibition 2 to 4 hours after clopidogrel intake. The mechanism probably involves synergistic increase in cAMP levels.

What is the first sign of kidney problems?

Signs and symptoms of acute kidney failure may include: Decreased urine output, although occasionally urine output remains normal. Fluid retention, causing swelling in your legs, ankles or feet. Shortness of breath.

Does clopidogrel affect blood pressure?

Arterial hypertension is associated with platelet activation, increased sCD40L levels and endothelial dysfunction suggesting that inhibition of platelet-derived sCD40L release may improve endothelial function and lower blood pressure (BP).