Quick Answer: How Fast Does High Grade Bladder Cancer Spread?

What is the most aggressive form of bladder cancer?

Small Cell Carcinoma of the Bladder This aggressive form of the disease begins in small nerve-like cells in the bladder called neuroendocrine cells.

Small cell carcinoma makes up about 1 percent of bladder cancers.

It is often detected at an advanced stage, after it has spread to other parts of the body..

What is the prognosis for high grade bladder cancer?

In patients with high-risk NMIBC, there is a consistent 30% to 35% initial treatment failure rate and about 50% of patients relapse at 5 years after treatment. Beyond 5 years, a consistent but slower failure rate of 4% has been observed and nearly 90% recur by 15 years.

Where does bladder cancer spread first?

Bladder cancer can spread this way. If it does, it usually first spreads to the lymph nodes in the pelvis, surrounding the bladder (called perivesicular lymph nodes). From there, it can spread to lymph nodes that are close to major blood vessels that run into the leg and pelvis.

What happens in the final stages of bladder cancer?

Cancer cells may have spread to organs close to the bladder or those further away, such as the liver or lungs. The signs and symptoms of bladder cancer that has spread to other parts of the body include: tiredness or weakness. pain when urinating.

Is high grade bladder cancer curable?

Unlike some patients diagnosed with bladder cancer after having it spread to other sites, when it’s too late to treat effectively, or those with low-grade tumors that are not likely to ever be aggressive, this is a potentially curable cohort of patients.

What stage is high grade bladder cancer?

Most commonly, people with high-grade noninvasive (stage 0a), carcinoma in situ (stage 0is), or non-muscle-invasive (stage I) bladder cancer are treated with TURBT, followed by local intravesical immunotherapy using Bacillus Calmette-Guerin (or BCG, see “Immunotherapy” in Types of Treatment).

Is bladder cancer an aggressive cancer?

It has not grown in toward the hollow part of the bladder, and it has not spread to the thick layer of muscle or connective tissue of the bladder (Tis, N0, M0). This is always a high-grade cancer (see “Grades,” below) and is considered an aggressive disease because it can often lead to muscle-invasive disease.

What is the life expectancy of someone with Stage 4 bladder cancer?

For bladder cancer, if the cancer has spread to the regional lymph nodes, the 5-year survival rate is 36.3 percent. If it has spread to a more distant site, the 5-year survival rate is 4.6 percent. There are still treatment options for this stage. Keep in mind that new treatments are always in development.

Is bladder cancer curable if caught early?

Most bladder cancers are diagnosed at an early stage, when the cancer is highly treatable. But even early-stage bladder cancers can come back after successful treatment. For this reason, people with bladder cancer typically need follow-up tests for years after treatment to look for bladder cancer that recurs.

How long can you live with stage 1 bladder cancer?

Stage 1. Around 80 out of 100 people (around 80%) survive their cancer for 5 years or more after they are diagnosed. Stage 1 means that the cancer has started to grow into the connective tissue beneath the bladder lining.

Does removing the bladder cure bladder cancer?

Removing part of the bladder is not a common operation for bladder cancer. It is usually used to treat the very rare type of cancer called adenocarcinoma of the bladder. After having a partial cystectomy, you can pass urine in the normal way.

Is bladder cancer fast growing?

High grade bladder cancer is likely to grow and spread quickly and become life threatening. High-grade cancers often need to be treated with chemotherapy, radiation or surgery. Low-grade cancers appear non-aggressive and have a low chance of becoming high grade. They are rarely life threatening.

What does high grade invasive bladder cancer mean?

High grade The cancer cells look very abnormal and grow quickly. They are more likely to spread both into the bladder muscle and outside the bladder. In non-muscle-invasive tumours, the grade may be low or high, while almost all muscle-invasive cancers are high grade.

Is bladder cancer a death sentence?

The general 5-year survival rate for people with bladder cancer is 77%. The overall 10-year survival rate is 70% and the overall 15-year survival rate is 65%. However, survival rates depend on many factors, including the type and stage of bladder cancer that is diagnosed.

Can you have bladder cancer for years and not know it?

Even after reporting the problem to their doctors, blood in the urine may be initially misdiagnosed as a symptom of post-menopausal bleeding, simple cystitis or as a urinary tract infection. As a result, a bladder cancer diagnosis can be overlooked for a year or more.